Louise has 20 years of experience in health economics, health technology assessment and health outcomes and an in-depth knowledge of the methods of HTA. She has advised clients on HTA strategy and evidence generation in a diverse range of clinical areas. Louise has specialist experience in the area of outcome measurement and valuation. She has been a member of the EuroQol Group, the organisation responsible for the development of the EQ-5D instruments, for most of her career and currently holds a position on the Board of Directors.

Cormac is an epidemiologist with several years’ experience of successfully delivering observational research projects for a variety of clients. His work has utilised real world data to contribute across the drug development process from establishing the clinical and economic burden of disease, to informing key parameters of cost-effectiveness models and monitoring the long term post-marketing safety and effectiveness of drugs. He has been published extensively across a range of clinical, therapeutic and methodological areas.

Donna has managed and delivered a wide range of projects to help pharmaceutical companies with their health economics and outcomes research needs as well as maximising market access/reimbursement for new pharmaceutical and diagnostic interventions. She has a proven history of successfully leading on client projects and performing effectively at all stages of the project cycle.

Megan has extensive experience working across a variety of stages of the drug development process, ranging from analysis of Phase I and III clinical trial data to conducting systematic literature reviews and network meta-analyses for health technology assessment submissions. Megan is familiar with a wide range of common and novel statistical methods used in the pharmaceutical industry and has experience using both frequentist and Bayesian frameworks. She is also proficient with a wide range of programming languages, including SAS, R and WinBUGs.

Rebecca has a background in medical writing and horizon scanning for HTA organisations as part of a national horizon scanning centre. She has experience of conducting systematic reviews, from conception to completion, planning and conducting a clinical trial and preparing oral and poster presentations for a variety of audiences. Rebecca has experience in several disease areas including musculoskeletal health, nutrition and gastrointestinal disease.

Jasmine’s main responsibility at PHMR is in project delivery and management for a range of activities in health economics, outcomes research and market access. Jasmine also contributes to PHMR’s operations and enjoys optimising organisation and communication for our projects to progress rapidly, efficiently and to the highest standards. She has an interest in HTA processes, market access and novel reimbursement frameworks for therapeutics with innovative mechanisms and those based on cell and gene therapies. Jasmine has over 10 years of experience in pharmacology, having previously worked in the UK and Europe for two world leading pharmaceutical companies. She has publications in several peer-reviewed journals and has presented at a range of international conferences. Jasmine has experience in the therapeutic fields of inflammation, allergy, stem cell therapies, oncology, pain and neuroscience.

Lefteris carries broad knowledge in health economics having served in multiple academic and commercial positions. He holds great experience with the collection, evaluation, and modelling of clinical and cost data having designed numerous clinical trial based economic evaluations and having led the development of multiple economic models for HTA submission purposes. He also carries great familiarity with HTA agency processes having been part of the technical teams supporting expert committees of UK NICE clinical guidelines.

Dave has considerable experience in the information and library field supporting health research. He is responsible for designing literature searches and strategies to support the wide variety of projects and research that PHMR undertakes and managing the results of searches using reference management software. He has run literature searches to support numerous reviews including NICE single and multiple technology assessments, Cochrane reviews, Public Health Research Council projects, and British Thoracic Society clinical guidelines.

Nicola has conducted focussed and pragmatic literature reviews and contributed to projects on clinical trial design and burden of illness studies, global HTA strategies and the use of patient reported outcome measures in HTA. Nicola has extensive experience in clinical trial method development and has developed skills in data extraction and data management, presenting reports in the form of slide decks or word documents, as well the preparation of manuscripts and posters.

Gabriel has experience in conducting multiple stages of systematic reviews from protocol development through to interpretation and communication of results in written format. He has contributed to reviews across a wide range of therapeutic areas which have been used to support strategic drug development, value message development, economic modelling, and to inform HTA submissions. In addition to systematic reviews, Gabriel has contributed to the development of dossiers and materials for publication and congress activities.

Thomas is a statistician and has been involved in a variety of projects using real-world data to inform decision making and insight. He has worked with a variety of frequentist and Bayesian modelling approaches with complex spatio-temporal data using state-of-the-art MCMC fitting procedures. He is proficient in R and Python. Currently, he is completing his PhD at Imperial College London after having a varied background in mathematics and statistics with applications in various areas. He has presented at conferences and workshops nationally and internationally and is published in peer-reviewed journals.

Helen is experienced in conducting systematic and pragmatic literature reviews (clinical and economic), and in developing value messages and global value dossiers. She has worked in the fields of immunology, molecular biology, physiology, and cell biology research. Helen has written and edited a wide range of medical documents, including published manuscripts, posters and oral presentations.

Aurelie is a health economist with experience of adapting and developing full cost-effectiveness models and budget impact models in various disease areas for HTA submission purposes. Aurelie has also contributed to projects of measurement and valuation of health-outcomes, developing mapping algorithms to generate utility data to inform cost-utility analysis. Prior to joining PHMR she conducted evaluative academic research on health policy in Australia, gaining experience in data analysis using econometrics methods, additionally she has previous work experience in marketing in the pharmaceutical industry.

Anne-Sophie has a wide-ranging experience of health economics and HTA in a range of settings including consultancies, hospitals, pharmaceutical companies and governmental bodies. Such wide-ranging experience has provided her with an in-depth understanding of HTA and reimbursement of pharmaceuticals. Anne-Sophie has developed many HTA submissions for the French HAS (Haute Autorité de Santé) for a range of new therapies including for oncology and orphan designation treatments on behalf of leading pharmaceutical companies. Prior to joining PHMR, Anne-Sophie worked at the Health Products Economics Committee (CEPS) of the French Ministry of Health where she developed valuable insight and experience in pricing processes and negotiations, and evaluation of economic dossiers.

While at PHMR, Ally has been involved in supporting targeted and systematic literature reviews, gathering and interpreting data and communicating complex information in the form of slide decks and scientific reports. She has experience in multiple project types including reviews of clinical efficacy, economic evaluations and burden of illness, HTA process reviews, and production of slide decks for training and educational use. She has disease area experience in oncology, muscle wasting, and rare diseases. Prior to joining PHMR, Ally worked in the pharmaceutical industry as a project manager and holds a PhD in cellular biology and tissue engineering.

Elaine is a medical statistician with extensive experience of statistical input into clinical trials and large public health projects. She possesses experience in analysis of trial data using advanced techniques, merging large patient data sets to assess public health interventions and is fully compliant with Good Clinical Practice (GCP) with up to date certification. This includes contributing to study design, protocol development and the writing of Statistical Analysis Plans (SAPs) as well as the analysis of data using a wide variety of statistical techniques.

Dimitris is a health economist, with broad experience in economic evaluations of therapeutic and diagnostic interventions. He has led and contributed to the conceptualisation and development of long-term models, in a wide range of software, and has completed projects for a diverse range of funders and clients including research foundations, pharmaceutical, and medical device companies.
He also has conducted systematic literature reviews, and diagnostic meta-analyses, and has broad knowledge of HTA methods and processes. His work covers a wide range of disease areas including oncology, mental health, and metabolic diseases.

Catherine’s main responsibility at PHMR is focussed on undertaking pragmatic and systematic literature reviews. Prior to joining PHMR, Catherine worked for 15 years in clinical trial management in an academic and commercial trial environment and was involved in Phase II/III trials across different therapeutic areas. She has developed skills in data monitoring, communication with commercial and academic sponsors and preparing/submitting complex study documentation. During her PhD, she prepared manuscripts for publication and has presented at international conferences.